diff --git a/core/autoload/packages.el b/core/autoload/packages.el
index 04278e50d..f79eb7e2e 100644
--- a/core/autoload/packages.el
+++ b/core/autoload/packages.el
@@ -108,7 +108,8 @@ Used by `doom/packages-autoremove'."
   (doom-initialize-packages t)
   (let ((package-selected-packages
          (append (mapcar 'car doom-packages) doom-core-packages)))
-    (package--removable-packages)))
+    (cl-set-difference (package--removable-packages)
+                       doom-protected-packages)))
 
 ;;;###autoload
 (defun doom-get-missing-packages ()
diff --git a/core/core-os.el b/core/core-os.el
index 1720d8479..181c87a77 100644
--- a/core/core-os.el
+++ b/core/core-os.el
@@ -3,6 +3,11 @@
 (defconst IS-MAC   (eq system-type 'darwin))
 (defconst IS-LINUX (eq system-type 'gnu/linux))
 
+;; In case this config is shared across multiple computers (like mine are),
+;; let's protect these from autoremoval.
+(push 'exec-path-from-shell doom-protected-packages)
+(push 'osx-clipboard doom-protected-packages)
+
  ;; clipboard
 (setq x-select-request-type '(UTF8_STRING COMPOUND_TEXT TEXT STRING)
       ;; Use a shared clipboard
diff --git a/core/core-packages.el b/core/core-packages.el
index d3a8cbdd8..a90538cb8 100644
--- a/core/core-packages.el
+++ b/core/core-packages.el
@@ -54,6 +54,9 @@ package's name as a symbol, and whose CDR is the plist supplied to its
   "A list of packages that must be installed (and will be auto-installed if
 missing) and shouldn't be deleted.")
 
+(defvar doom-protected-packages nil
+  "A list of packages that shouldn't be deleted by `doom/packages-autoremove'.")
+
 (defvar doom-init-time nil
   "The time it took, in seconds, for DOOM Emacs to initialize.")